Who are the Top Big Pharma Dealmakers by Volume, and How Does Their in-Licensing Activity Compare With out-Licensing? – Research and Markets

DUBLIN, July 20, 2016 /PRNewswire/ —

Research and Markets has announced the addition of the “Big Pharma Licensing Trends, 2011-15” report to their offering.

Key to predicting future trends in Big Pharma deal-making is reviewing the peer set’s most recent activity. Between 2011 and 2015, Big Pharma – a peer set of approximately 16 firms across the world with large R&D and sales organizations, and sales valued at $10bn or more – signed over 1,100 drug-focused deals, growing at a compound annual growth rate of 10%. Overall, Big Pharma represented the majority of the monetary value of all biopharma partnerships: the peer group was responsible for $133bn of deal-making during the five-year period versus the $254bn in all comparable biopharma alliances (including the Big Pharma peer set).

As of mid-2015, Big Pharma companies had in the pipeline for cancer approximately 279 candidates, which is well over two times that of any other therapeutic area. This was reflected in deal-making; between 2011 and 2015, nearly two-thirds of Big Pharma’s in- and out-licensing deals were in oncology, and immuno-oncology was the key driver of oncology in-licensing.

This report addresses the following questions:

– Who are the top Big Pharma dealmakers by volume, and how does their in-licensing activity compare with out-licensing?

– How has the emergence of immuno-oncology affected overall oncology dealmaking and values?

– Besides oncology, what therapeutic areas are driving Big Pharma dealmaking and why?

– What therapeutic areas and deal structures are driving Big Pharma out-licensing?

– At what stages of development does the Big Pharma peer set tend to partner, and what are the average payments per phase?

Key Topics Covered:

Executive Summary

Key Points and Overall Totals

1. Deal volume increased but Big Pharma’s overall share was small

2. Big Pharma represented the majority of deal-making spend

3. 2014 and 2015 were stand-out years in Big Pharma deal-making

4. Bibliography

Company Analysis and Case Studies

5. AstraZeneca was the leading dealmaker by overall volume within the Big Pharma peer set

6. Johnson & Johnson signed key cancer deals and formed an innovation initiative

7. Roche continued oncology momentum but deal-making showed importance of other therapeutic areas

8. Pfizer’s in-licensing fluctuated while out-licensing efforts increased

9. Overall, out-licensing increased by 42% and Amgen and Eli Lilly evenly split in- and outlicensing

10. Bibliography

Therapy Area Analysis

11. Oncology dominated Big Pharma deal volume

12. Infectious disease agreements declined, but there is potential for a turnaround

13. Endocrine, metabolic, and genetic disorders gained speed

14. Oncology also led in terms of partnership dollar values

15. Oncology was also the focus of most out-licensing deals

16. Bibliography

Deal Economics

17. Johnson & Johnson was the top dealmaker by dollars spent within the Big Pharma peer set

18. Payment metrics on deals generally increased

19. Average deal values increased

20. A higher proportion of deal value was still locked up in milestones

21. There were more than two-dozen billion-dollar deals between 2011 and 2015

Phase Analysis

22. Early-stage candidates dominated partnerships

23. Marketed drugs and Phase II candidates led in aggregate up-front payments

24. Phase II and marketed drugs tended to have higher average up-fronts

Geographic Breakdown of Deal-Making

25. Regional deal-making took off

26. Bibliography

Deal Structures

27. R&D was the most common component of deal structures

28. Option-based deal-making decreased

29. Bibliography

Appendix

For more information visit http://www.researchandmarkets.com/research/wljfv7/big_pharma

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