Big Movers: CTI BioPharma Corp. (NASDAQ:CTIC), ProQR Therapeutics N.V. (NASDAQ:PRQR), InnerWorkings Inc. (NASDAQ:INWK), NICE Systems Ltd. (NASDAQ:NICE),

Ladenburg Thalmann lowered shares of CTI BioPharma Corp (NASDAQ:CTIC) from a buy rating to a neutral rating in a research note issued to investors on Wednesday, The Fly reports.

CTI BioPharma Corp. (NASDAQ:CTIC) belongs to Healthcare sector. Its weekly performance is -5.88%. On last trading day company shares ended up at $0.60. CTI BioPharma Corp. (NASDAQ:CTIC) distance from 50-day simple moving average (SMA50) is 2.58%.

ProQR Therapeutics N.V. (NASDAQ:PRQR) announced details about the Research & Development Day to be held on Monday, March 14, 2016 in New York, NY, USA starting at 10am ET. Daniel de Boer, Chief Executive Officer of ProQR will also take part in an analyst led fireside chat at the Barclays Global Healthcare Conference on Tuesday, March 15, 2016 at the Loews Miami Beach Hotel in Miami Beach, FL, USA at 2:35pm ET.

ProQR Therapeutics N.V. (NASDAQ:PRQR) shares increased 0.46% in last trading session and ended the day at $4.40. PRQR return on assets is -19.20%. ProQR Therapeutics N.V. (NASDAQ:PRQR) quarterly performance is -53.68%.

InnerWorkings Inc. (NASDAQ:INWK) reported it generated $1.03 billion and $1.09 billion in constant currency in 2015, reflecting 9.3% growth in constant currency over 2014. Furthermore, net cash provided by operating activities in 2015 was $43.4 million, compared to net cash used for operating activities of $12.5 million in 2014

On 03 March, InnerWorkings Inc. (NASDAQ:INWK) shares decreased -3.92% and was closed at $6.61. INWK EPS growth in last 5 year was -35.30%. InnerWorkings Inc. (NASDAQ:INWK) year to date (YTD) performance is -11.87%.

NICE Systems Ltd. (NASDAQ:NICE) announced on February 23 that it was presented with the “Most Innovative Use of Technology” award from Wall Street Letter, a publication of Pageant Media for the second year in a row.

NICE Systems Ltd. (NASDAQ:NICE) ended the last trading day at $61.14. Company weekly volatility is calculated as 1.87% and price to cash ratio as 8.45. NICE Systems Ltd. (NASDAQ:NICE) showed a weekly performance of 0.48%.

The Valspar Corporation (NYSE:VAL) will begin trading ex-dividend on March 03, 2016. A cash dividend payment of $0.33 per share is scheduled to be paid on March 18, 2016. Shareholders who purchased VAL prior to the ex-dividend date are eligible for the cash dividend payment. This represents an 10% increase over the same period a year ago.

The Valspar Corporation (NYSE:VAL) shares increased 0.65% in last trading session and ended the day at $80.94. VAL Gross Margin is 36.40% and its return on assets is 8.20%. The Valspar Corporation (NYSE:VAL) quarterly performance is -3.59%.

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